1H-MRS quantification of tNA and tCr in patients with multiple sclerosis: a meta-analytic review

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1H-MRS quantification of tNA and tCr in patients with multiple sclerosis: a meta-analytic review.

Meta-analysis was performed on the results of 75 comparisons from the 30 peer-reviewed publications that used proton magnetic resonance spectroscopy (1H-MRS) or spectroscopic imaging to (i) quantify the mean concentrations of total creatine (tCr, found in neurons, astrocytes and oligodendrocytes), and/or total N-acetyl groups (tNA, found only in neurons), in the lesional and/or non-lesional whi...

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H-MRS quantification of tNA and tCr in patients with multiple sclerosis: a meta-analytic review

Meta-analysis was performed on the results of 75 comparisons from the 30 peer-reviewed publications that used proton magnetic resonance spectroscopy (H-MRS) or spectroscopic imaging to (i) quantify the mean concentrations of total creatine (tCr, found in neurons, astrocytes and oligodendrocytes), and/or total N-acetyl groups (tNA, found only in neurons), in the lesional and/or non-lesional whit...

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Background: Multiple Sclerosis (MS) is considered as one of the most prevalent chronic and progressive neurological diseases that has high simultaneity with some psychological disorders such as depression and anxiety; we examined depression and anxiety in people suffering from MS in this review study.  Methods: We conducted this study using a systematic review method relying on the search from...

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ژورنال

عنوان ژورنال: Brain

سال: 2005

ISSN: 1460-2156,0006-8950

DOI: 10.1093/brain/awh640